文献详情
Influence of Syringe Volume on Foam Stability in Sclerotherapy for Varicose Vein Treatment
文献类型期刊
作者Bai, Taoping[1];Jiang, Wentao[2];Fan, Yubo[3]
机构
通讯作者Jiang, WT (reprint author), Sichuan Univ, Dept Appl Mech, NanYihuan Rd 24, Chengdu 610065, Sichuan, Peoples R China.
来源信息年:2018  卷:44  期:5  页码范围:689-696  
期刊信息DERMATOLOGIC SURGERY影响因子和分区  ISSN:1076-0512
关键词morrhuate sodium; sclerosing agent, chemical model; devices; drug stability; half life time; human; injection; phase transition; saphenous vein; sclerotherapy; surgery; syringe; temperature; treatment outcome; varicosis, Drug Stability; Half-Life; Humans; Injections; Models, Chemical; Phase Transition; Saphenous Vein; Sclerosing Solutions; Sclerotherapy; Sodium Morrhuate; Syringes; Temperature; Treatment Outcome; Varicose Veins
增刊正刊
摘要BACKGROUND Despite the popularity of sclerotherapy for treating varicose veins, it still exhibits various problems, such as pulmonary embolism, deep-vein thrombosis, phlebitis, and visual disorders. OBJECTIVE To investigate syringe volume influence on foam stability, obtain the foam decay rule, and provide a reference for clinics. MATERIALS AND METHODS Five types of syringes are used to prepare foam at room temperature with various liquid-gas ratios. Foam decay process experiments were performed 5 times and recorded by video. The stability indices used include drainage time, half-life, bubble diameter, bubble surface density, and drainage rate. RESULTS The 30 and 2-mL syringes, respectively, recorded the highest and lowest drainage speeds. Foam drainage time and half-life, differences varied between 15 and 70 seconds, and 20 and 100 seconds, respectively. Foam bubble diameters were distributed over 0.1 to 2.0 mm with roughly 200 to 700 bubbles per square centimeter. CONCLUSION Increased syringe volume causes the bubble diameter to increase. Thus, foam dispersion increases and foam half-life decreases; hence, foam becomes unstable. It is, thus, better to use a small syringe several times to prepare foam in clinics using segmented injections.
收录情况SCIE(WOS:000440272000012)  PubMed(29140865)  
所属部门生物与医学工程学院
链接地址https://www.scopus.com/inward/record.uri?eid=2-s2.0-85048983862&doi=10.1097%2fDSS.0000000000001402&partnerID=40&md5=df176b1209c6fb3c72d4547b0913f0ae
DOI10.1097/DSS.0000000000001402
百度学术Influence of Syringe Volume on Foam Stability in Sclerotherapy for Varicose Vein Treatment
语言外文
人气指数76
浏览次数76
基金Application of Basic Research Projects of Science and Technology Department of Sichuan Province, China [2016JY0182]
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